Basic Information
VIS ID
TVIS10017494
Fusion event
HBV-chr9 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;Polymerase;
Start
1581
Integrated sequence
CTACCGTCCCCTTCTTCGTCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTG| |CACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAAT
Host Sequence
Chromosome
chr9
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
11203/11203 (Hg38)
End
11203/11203 (Hg38)
Location type
upstream
Nearest miRNA
hsa-let-7a-1/Downstream/18941;
Nearest TSS
ENST00000422679/Downstream/16454;
Nearest CpG islands
None/Target, None/Upstream, chr9-CpG: 64/Downstream/17646
Nearby gene
DDX11L5(+) ;
Upstream sequence
GTATGGTCCTCCCTAGGAGGAGTTGGCCAGGCTAATGGAGGCAGCCCATGGGTAATGGACCAACCAACGGCCCCTGTGGAGTTCCACTGCCCTGCCTGGA
Downstream sequence
aggactggaacccaggtctgaatccagagcctgtTTTTAACTAATATGCCCATGAttttttttttttttttttttttttttttgagatggggtctcactc
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate