VISDB Viral Integration Site DataBase

VIS ID

TVIS10017496

Fusion event

HBV-MORF4L2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

Polymerase;

Start

1308

Integrated sequence

GGGCTTGGCCATAGGCCATCAGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGG| |TCTGGGGCGAAACTGCTCGGCACCGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGC

Chromosome

chrX

Cytoband

q22.2

Reference genome

Start

End

102930563/103675635 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-142-3p ; hsa-mir-652-3p ; hsa-mir-505-3p ; hsa-mir-100-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-4668-5p ; hsa-mir-498 ; hsa-mir-3682-5p ; hsa-mir-767-5p ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-1276 ; hsa-mir-7855-5p ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-5000-3p ; hsa-mir-4436a ; hsa-mir-4700-3p ; hsa-mir-5683 ; hsa-mir-4511 ; hsa-mir-548b-3p ; hsa-mir-522-3p ; hsa-mir-224-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-6073 ; hsa-mir-5191 ; hsa-mir-3914 ; hsa-mir-4789-3p ; hsa-mir-6776-3p ; hsa-mir-1273h-3p ; hsa-mir-2392 ; hsa-mir-2467-3p ; hsa-mir-3605-5p ; hsa-mir-3678-3p ; hsa-mir-376c-3p ; hsa-mir-5009-5p ; hsa-mir-6847-5p ; hsa-mir-8058

Nearest miRNA

hsa-let-7f-2/Upstream/8612409; hsa-mir-105-1/Downstream/2964179;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/45886, chrX-CpG: 38/Downstream/11544

Upstream sequence

aaatactatgtagccataaaaaatgatgagttcatgtcctttgtagggacatggatgaagctggaaaccatcattctcagcaaactattgcaaggacaaa

Downstream sequence

AAACCATGAAACAAATCACCATCCTTCAACAATTTGAGCAAAGATAGAATGCCTAAGAACAACATAGATGGACTTGCAGAGGATGGGCTGTTTTACTTCA