VISDB Viral Integration Site DataBase

VIS ID

TVIS10017498

Fusion event

HBV-RANBP10 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1834

Integrated sequence

AGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGC| |CTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTT

Chromosome

chr16

Cytoband

q22.1

Reference genome

Start

End

67813472/67779569 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-330-5p ; hsa-mir-615-3p ; hsa-mir-186-5p ; hsa-mir-15b-5p ; hsa-mir-222-3p ; hsa-mir-6510-5p ; hsa-mir-3175 ; hsa-mir-6864-5p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-3179 ; hsa-mir-7515 ; hsa-mir-873-3p ; hsa-mir-6857-3p ; hsa-mir-4499

Nearest miRNA

hsa-mir-1225/Upstream/577174; hsa-mir-11401/Downstream/453857;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/60026, chr16-CpG: 69/Downstream/26803

Upstream sequence

TCCAAGGTGGAATGGCCAACGTGTGGCCTCAGTGTGGTGGCCGTCTGGGGTGGGTGTGGGCTGCCCGCCTAGTGACCCTGGGAGGCAGAAGTTTCTTTGC

Downstream sequence

ACTGACACTACCCTTCCTCTATTGATCTCTGCAGGCACCTGAATATGGCTGAGTTATTAGGAGCTCTTGGGTCCTTGCTAACGTTGAGTAATTCAGTAAA