ANKRD31 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017501
Fusion event
HBV-ANKRD31 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;
Start
1808
Integrated sequence
CAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCA| |GCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACAT
Host Sequence
Chromosome
chr5
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
74519489/75223664 (Hg38)
End
74519489/75223664 (Hg38)
Location type
Intronic
Target gene
ANKRD31
miRNAs that regulate target gene
hsa-mir-7-5p
Nearest miRNA
hsa-mir-10397/Upstream/2345001; hsa-mir-103a-1/Downstream/7616491;
Nearest TSS
ENST00000502646/Upstream/54499; ENST00000442032/Downstream/13214;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/169250, chr5-CpG: 41/Downstream/13137
Upstream sequence
AAGCAAACGTTCTTCATACTTTTAAATTTCCCAGATGATTAATCACCTGCCCGCATTGATAGTCATTTTTCCTCCCTAAAAAAATACAATTCCCTTATTT
Downstream sequence
TAGTAAACAGCTtgttatcgactgaatgtctgtgcacacccgccccagccaaattcatatgctgatgccctaaccgccaatgtgatgatattagaaggta
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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