VISDB Viral Integration Site DataBase

VIS ID

TVIS10017503

Fusion event

HBV-PHTF2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1709

Integrated sequence

GGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTC| |AAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAG

Chromosome

chr7

Cytoband

q11.23

Reference genome

Start

End

77507900/77878583 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-let-7a-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-590-3p ; hsa-mir-548t-5p ; hsa-mir-5589-3p ; hsa-mir-548az-5p ; hsa-mir-8055 ; hsa-mir-30a-5p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-186-5p ; hsa-mir-30e-5p ; hsa-mir-92b-3p ; hsa-mir-4329 ; hsa-mir-3653-5p ; hsa-mir-3672 ; hsa-mir-676-5p ; hsa-mir-4495 ; hsa-mir-6864-3p ; hsa-mir-802 ; hsa-mir-5096 ; hsa-mir-513b-5p ; hsa-mir-27b-5p ; hsa-mir-627-3p ; hsa-mir-556-5p ; hsa-mir-873-3p ; hsa-mir-3140-5p

Nearest miRNA

hsa-mir-10525/Upstream/1963314; hsa-mir-10399/Downstream/14325432;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/79050, chr7-CpG: 140/Downstream/140551

Upstream sequence

attactgtgaaaagtcatcatcaggaaggctagggcccctgtcccccatctcagtaggtgggtagaatcctaacttgtcaactcacaaacacagctggcc

Downstream sequence

ttttgggaagggctgttatcatccttcctttaaactataaactaaattccttccaaagttagcttggctactcccaggaatgaacaagcacagcttggag