VISDB Viral Integration Site DataBase

VIS ID

TVIS10017505

Fusion event

HBV-PDE3A integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

337

Integrated sequence

ACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTTGCAGTCCCCAACCTCCAATCACTCA| |CCAACCTCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGT

Chromosome

chr12

Cytoband

p12.2

Reference genome

Start

End

20704464/20551530 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-128-3p ; hsa-mir-211-5p ; hsa-mir-3680-3p ; hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-3915 ; hsa-mir-1224-5p ; hsa-mir-6797-3p ; hsa-mir-6076 ; hsa-mir-3928-3p ; hsa-mir-5582-3p ; hsa-mir-8055 ; hsa-mir-129-5p ; hsa-mir-4776-3p ; hsa-mir-1304-5p ; hsa-mir-4677-5p ; hsa-mir-192-3p ; hsa-mir-2116-5p ; hsa-mir-22-5p ; hsa-mir-3613-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-8485 ; hsa-mir-7150 ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-7843-3p ; hsa-mir-5585-5p ; hsa-mir-3191-5p ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-942-5p ; hsa-mir-5588-5p ; hsa-mir-4799-3p ; hsa-mir-4720-5p ; hsa-mir-3128 ; hsa-mir-6824-3p ; hsa-mir-6764-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-518c-5p ; hsa-mir-6814-5p ; hsa-mir-3614-3p ; hsa-mir-7849-3p ; hsa-mir-6818-3p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-377-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6846-3p ; hsa-mir-4743-3p ; hsa-mir-6888-3p ; hsa-mir-3182 ; hsa-mir-3120-5p ; hsa-mir-1237-3p ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-361-5p ; hsa-mir-3171 ; hsa-mir-2115-3p ; hsa-mir-1265 ; hsa-mir-5692a ; hsa-mir-106a-3p ; hsa-mir-6844 ; hsa-mir-4684-3p ; hsa-mir-103a-2-5p ; hsa-mir-8066 ; hsa-mir-1267 ; hsa-mir-3147 ; hsa-mir-367-5p ; hsa-mir-4328 ; hsa-mir-4425 ; hsa-mir-450a-1-3p ; hsa-mir-4652-3p ; hsa-mir-4747-5p ; hsa-mir-5196-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/2878136; hsa-let-7i/Downstream/3660891;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/181342, chr12-CpG: 97/Downstream/61

Upstream sequence

GAATATTCCACAAAGAGAAAAATTATCATTAAAAACTTTGAACATCAggctgggtatgatgactcacgcctgtaatcccagcactctgggaggctgcagc

Downstream sequence

GTTAATTGAGCTGTTTAAATGTCAGAAGTTATTTTTGTTAAAAACTAGGAAGAAAGTTTCTTCAATTTTTCCATTATGTTTTTAAGTTTTCAAGGCTAGT