VISDB Viral Integration Site DataBase

VIS ID

TVIS10017506

Fusion event

HBV-GLCE integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

799

Integrated sequence

GTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAACATCTTGAATCCCTTTTTACCGCTG| |TTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTACTAAAACTAAACGTTGGGGCTACTCCCTTAACTTCATGGGATATGTAATTGGAAGTTG

Chromosome

chr15

Cytoband

q23

Reference genome

Start

End

69563770/69271431 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-30b-5p ; hsa-mir-218-5p ; hsa-mir-484 ; hsa-mir-143-5p ; hsa-mir-485-5p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-3929 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-6884-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-512-3p ; hsa-mir-520f-3p ; hsa-mir-562 ; hsa-mir-636 ; hsa-mir-1273e ; hsa-mir-4473 ; hsa-mir-142-3p ; hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-302c-3p ; hsa-mir-4795-5p

Nearest miRNA

hsa-mir-10393/Upstream/469506; hsa-mir-11181/Downstream/807941;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/109831, chr15-CpG: 73/Downstream/27369

Upstream sequence

aaatatttttatatgatgcttaatttatgatgaagtcaaatatatatattAATTTATGACAAAGTCAAATACACACACAGatatatatatatatatatat

Downstream sequence

agcattcaagtgattctgatgcaggtgagctgggggcatacagggaggaacactgCCCTGGACTATCCATTGCATTTTTGCCTCTAAACAACTACAGAAT