VISDB Viral Integration Site DataBase

VIS ID

TVIS10017507

Fusion event

HBV-REV1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

Polymerase;

Start

1284

Integrated sequence

TGCTGACGCAACCCCCACTGGTTGGGGCTTGGCCATAGGCCATCAGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTA| |GCAGCTTGTTTTGCTCGCAGCCGGTCTGGGGCGAAACTGCTCGGCACCGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAG

Chromosome

chr2

Cytoband

q11.2

Reference genome

Start

End

100020225/99403762 (Hg38)

Location type

Exonic

Fragile sites / regions

FRA2S ; FRA2A

Target gene

miRNAs that regulate target gene

hsa-mir-96-5p ; hsa-mir-21-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-155-5p

Nearest miRNA

hsa-mir-1285-2/Upstream/2605409; hsa-mir-10b/Downstream/1905688;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/65825, chr2-CpG: 202/Downstream/85319

Upstream sequence

agtgttattatagttagggttaccgtattttatgtgtggcccaagacaattcttcttcttccaatgtggcccagggaagcaaaaagactggactcccctg

Downstream sequence

TTCAGCTCCCTCTGAAGTTCAGCAGGAAGGGCAGCAAATACCTCAGGGTCCACCTAGTGGAAAAGACGAGGTCAAAGTCAAACCTGAGCTAATTGTAGAT