VISDB Viral Integration Site DataBase

VIS ID

TVIS10017509

Fusion event

HBV-NR3C2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

458

Integrated sequence

TGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAG| |GTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCC

Chromosome

chr4

Cytoband

q31.23

Reference genome

Start

End

149181270/148260118 (Hg38)

Location type

splicing

Target gene

miRNAs that regulate target gene

hsa-mir-19b-3p ; hsa-mir-135a-5p ; hsa-mir-124-3p ; hsa-mir-335-5p ; hsa-mir-148b-3p ; hsa-mir-944 ; hsa-mir-548i ; hsa-mir-301b-3p

Nearest miRNA

hsa-mir-12113/Upstream/477450; hsa-mir-1305/Downstream/4229209;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/527351, chr4-CpG: 294/Downstream/181942

Upstream sequence

TTTTTATTTCCAACAGGTCATGGATTGACGGCAGTCAAGGAAAAAGCAGGAGCCACTCTACGGATTCATGGTGTAAATTCTGGATCTTCTGAAGGAGCCC

Downstream sequence

TGGGGAAAGAAATTGAGATTTAAATAACTACACCGTAAAGGCACATTTAACATGCTGCACAGCTTAGCTCAAAATTTGTCAATAATCATGGTTCGATACA