VISDB Viral Integration Site DataBase

VIS ID

TVIS10017513

Fusion event

HBV-ATE1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1832

Integrated sequence

GGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCT| |GCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGC

Chromosome

chr10

Cytoband

q26.13

Reference genome

Start

End

123534592/121775077 (Hg38)

Location type

Intronic

Fragile sites / regions

FRA10D ; FRA10F ; FRA10A ; FRA10B

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-130b-3p ; hsa-let-7b-5p

Nearest miRNA

hsa-mir-107/Upstream/1816485; hsa-mir-202/Downstream/641888;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/165858, chr10-CpG: 125/Downstream/152380

Upstream sequence

ACACCTTGTAATATGTCACAGCCTCTTCAAGCAAATCAAGAATACCAAGACTCACTCAGATATGAAGTTAGTTTTTGGATCACTGGCTTCTTCAGAGAGA

Downstream sequence

TGGACCTGCCCCCAGCCGCTTTGCAGCCTGCCGCCCCCTCCTCATCAATTGCACAGCCGTCGACTTCTTCCTTACATTCCCACAGCTCCCTGGCCGGGAC