Basic Information
VIS ID
TVIS10017514
Fusion event
HBV-LINC01164 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
core protein;X protein;
Start
1817
Integrated sequence
TGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGC| |AACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTA
Host Sequence
Chromosome
chr10
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
133619808/131787472 (Hg38)
End
133619808/131787472 (Hg38)
Location type
ncRNA
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
LINC01164
Nearest miRNA
hsa-mir-107/Upstream/824804; hsa-mir-202/Downstream/1460039;
Nearest TSS
ENST00000439456/Upstream/475751; ENST00000634373/Downstream/2727;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/111217, chr10-CpG: 20/Downstream/24744
Upstream sequence
attgaatggaccgaatggaatcaacatcaaacttaatcaaacggaattatcgaatggaatcggaaagaatcatcgaatggccacgaatggaatcatctaa
Downstream sequence
AAACTGGACTTCCCTTGACCTATAAATATGTTTATATGTTTTAAGGTAGTAAAATGCCAGTGTTTACTTCTGGCTGCAGTGTATCCTATCTATCCTAGTT
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate