VISDB Viral Integration Site DataBase

VIS ID

TVIS10017516

Fusion event

HBV-CKAP5 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;

Start

1886

Integrated sequence

GCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTG| |GGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGTGA

Chromosome

chr11

Cytoband

p11.2

Reference genome

Start

End

46804670/46783120 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-130b-3p ; hsa-mir-34a-5p ; hsa-mir-103a-3p ; hsa-mir-21-5p ; hsa-mir-18a-5p ; hsa-mir-16-5p ; hsa-mir-484 ; hsa-mir-186-5p ; hsa-mir-15b-5p

Nearest miRNA

hsa-mir-129-2/Upstream/29928; hsa-let-7a-2/Downstream/396491;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/77633, chr11-CpG: 93/Downstream/62523

Upstream sequence

ACTGGGTGTTGAGCTTCTTAGTGTACTCCTCGAGAGCGCTCAGGAAGCTGACCTTGAAGCTCTCCAGCACGGGCAGCAGGCCTTGGCGGAGGTCCTCGAG

Downstream sequence

CGCGGGCTTGGCCTTCTCGCTGAGCGTGCTCAGATGCTCGGTGGCCTTGGCGTGGTACTCGGCCAGTCTGGCGCCGCCGTTCTCCTTGAGAGCCTCAAGG