VISDB Viral Integration Site DataBase

VIS ID

TVIS10017517

Fusion event

HBV-SLCO1B3 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1773

Integrated sequence

TCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTAC| |TGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCC

Chromosome

chr12

Cytoband

p12.2

Reference genome

Start

End

21028449/20875515 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6867-3p ; hsa-mir-188-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-532-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-4639-3p ; hsa-mir-4457 ; hsa-mir-3936 ; hsa-mir-1277-5p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-5011-5p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-190a-3p ; hsa-mir-340-5p ; hsa-mir-5590-3p ; hsa-mir-142-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/3202121; hsa-let-7i/Downstream/3336906;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/322445, chr12-CpG: 34/Downstream/562020

Upstream sequence

tattccctttatccccaaaggcctcagtgagctcctaaatatccttcctcagattctacagaacagtatttccatacttctcaattgaaagaaaagttta

Downstream sequence

ACCAAAGGCATGGGGTTTACTCAGACCCCTGACAACATAAAGGCCTTGGCTGCTTTTCCTGTTTTTCTTTAGATCTGAGAGGCAGCGTGTGAAGCTgtta