VISDB Viral Integration Site DataBase

VIS ID

TVIS10017519

Fusion event

HBV-RPS19 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1734

Integrated sequence

GTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGG| |AGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGC

Chromosome

chr19

Cytoband

q13.2

Reference genome

Start

End

42373182/41869112 (Hg38)

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-193b-5p ; hsa-mir-501-5p ; hsa-mir-3591-5p ; hsa-mir-6806-5p ; hsa-mir-142-3p ; hsa-mir-6840-3p ; hsa-mir-874-5p ; hsa-mir-648 ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-548at-5p ; hsa-mir-4477a ; hsa-mir-1827 ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-566 ; hsa-mir-6789-3p ; hsa-mir-661 ; hsa-mir-4252 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-4486 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-652-3p ; hsa-mir-508-5p

Nearest miRNA

hsa-mir-10395/Upstream/1499205; hsa-let-7e/Downstream/515;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/8417, chr19-CpG: 144/Downstream/13686

Upstream sequence

acctttggatagcctacatcaattagcaacgcttgggaaacaggcaagtgagcagagctgccaagtgggcagggcagaggcgtgggtgggagacagcagg

Downstream sequence

CGGCGTCATGCCCAGCCACTTCAGCCGAGGCTCCAAGAGTGTGGCCCGCCGGGTCCTCCAAGCCCTGGAGGGGCTGAAAATGGTGGAAAAGGACCAAGAT