VISDB Viral Integration Site DataBase

VIS ID

TVIS10017520

Fusion event

HBV-APOE integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

316

Integrated sequence

GTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTTGCAG| |TCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGC

Chromosome

chr19

Cytoband

q13.32

Reference genome

Start

End

45412321/44909064 (Hg38)

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-199a-5p ; hsa-mir-1908-5p ; hsa-mir-199a-3p

Nearest miRNA

hsa-mir-10395/Upstream/150343; hsa-let-7e/Downstream/527590;

Nearest TSS

Nearest CpG islands

chr19-CpG: 90/Target, None/Upstream, None/Downstream

Upstream sequence

atcgcgtcattgcactctagtctggacgacactctgtctaaaaaataaataataattattattattatttaatttttattgagtaaaagatacattcagt

Downstream sequence

GTGCGCGCCAAGCTGGAGGAGCAGGCCCAGCAGATACGCCTGCAGGCCGAGGCCTTCCAGGCCCGCCTCAAGAGCTGGTTCGAGCCCCTGGTGGAAGACA