VISDB Viral Integration Site DataBase

VIS ID

TVIS10017521

Fusion event

HBV-RPS9 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;Polymerase;

Start

1531

Integrated sequence

CCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCGTCTGCCGTTCCGGCCGACCACGGGGCGCACCT| |CTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGA

Chromosome

chr19

Cytoband

q13.42

Reference genome

Start

End

54711383/54207515 (Hg38)

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1296-5p ; hsa-mir-935 ; hsa-mir-423-5p ; hsa-mir-766-3p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-mir-342-3p ; hsa-mir-328-3p ; hsa-mir-149-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-153-3p ; hsa-mir-6888-5p ; hsa-mir-6875-3p ; hsa-mir-4642 ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-6851-3p ; hsa-mir-1256 ; hsa-mir-6886-3p ; hsa-mir-6515-3p ; hsa-mir-1248 ; hsa-mir-877-3p ; hsa-mir-5088-3p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p

Nearest miRNA

hsa-let-7e/Upstream/225118; hsa-mir-10394/Downstream/74594;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/8, chr19-CpG: 54/Downstream/207714

Upstream sequence

accccaagggatcagccgtctcggcctcccacaatgctgggattaaaggcgtgagccaccgcgcccggccTCAACTGGAAGGCTTTAAGTGAGAGATGGG

Downstream sequence

AAGAATGCCAAGAAGGGCCAGGGTGGGGCTGGGGCTGGAGACGACGAGGAGGAGGATTAAGTCCACCTGTCCCTCCTGGGCTGCTGGATTGTCTCGTTTT