VISDB Viral Integration Site DataBase

VIS ID

TVIS10017522

Fusion event

HBV-USP34 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1691

Integrated sequence

CACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACC| |GACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATA

Chromosome

chr2

Cytoband

p15

Reference genome

Start

End

61415522/61188387 (Hg38)

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-23a-3p ; hsa-mir-19b-3p ; hsa-mir-127-5p ; hsa-mir-485-5p ; hsa-mir-218-5p

Nearest miRNA

hsa-mir-1301/Upstream/800942; hsa-mir-10b/Downstream/1017439;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/10161, chr2-CpG: 154/Downstream/281835

Upstream sequence

TAGTAGGAAGACCAGCTTTTTGCTCAGTCTTCTACAGTTTTCTCTCTTTCAATGAGGCACTTTGGCGTATCTTAAATTTCAATGAACACAAACAACTTTC

Downstream sequence

TCTTTAAATTCTTTACAATCGTCATATCTACCATTGTTGGACTGTTCTTCTGCATGCTGTGACCTGATATTTGACATGTCTTCTGAAAACGAAGATGGAA