Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene1380990113849247139964431387371513876010138654011386668413868202138691991386332413863594138779551387810413903172
SEL1L2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017524
Fusion event
HBV-SEL1L2 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;
Start
1811
Integrated sequence
AGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCA| |CCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGA
Host Sequence
Chromosome
chr20
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
13883818/13903172 (Hg38)
End
13883818/13903172 (Hg38)
Location type
Intronic
Target gene
SEL1L2
Nearest miRNA
hsa-mir-103a-2/Upstream/3253477; hsa-mir-1-1/Downstream/4567443;
Nearest TSS
ENST00000382410/Upstream/32958; ENST00000492055/Downstream/15951;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/117909, chr20-CpG: 101/Downstream/91950
Upstream sequence
ccacaagactgaggctccatctcaaaaaaaaaaaaaagaaagaaagaaaaaaGAAAAAAAAATCtggtttactgctaaatgtttaatgacaccttctcaa
Downstream sequence
acttttaatgatttcaacagttctgataattaccattgttatgactctagataaattgctactatttgctgttgcttaatttagatatttcacacattat
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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