VISDB Viral Integration Site DataBase

VIS ID

TVIS10017528

Fusion event

HBV-BTD integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1822

Integrated sequence

TTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTT| |TTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAG

Chromosome

chr3

Cytoband

p25.1

Reference genome

Start

End

15673652/15632145 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-340-5p ; hsa-mir-4729 ; hsa-mir-10b-3p ; hsa-mir-664a-3p ; hsa-mir-6516-5p ; hsa-mir-1273e ; hsa-mir-6499-3p ; hsa-mir-4722-5p ; hsa-mir-2467-3p ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-4649-3p ; hsa-mir-1247-3p ; hsa-mir-4768-3p ; hsa-mir-4257 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-302f ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-3942-3p ; hsa-mir-5100 ; hsa-mir-4670-3p ; hsa-mir-6837-3p ; hsa-mir-3620-3p ; hsa-mir-5584-3p ; hsa-mir-148a-5p ; hsa-mir-7160-5p ; hsa-mir-6125 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-570-3p ; hsa-mir-367-5p ; hsa-mir-1267

Nearest miRNA

hsa-mir-12127/Upstream/135837; hsa-let-7g/Downstream/65153;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/30071, chr3-CpG: 142/Downstream/226845

Upstream sequence

CCCCTCCTCTGCTCCACCCCCAGCCACGCACCTTTTCATGATGTGCTTGCCCACCTCTGTGGAGCCTGTGAACCCGATTTTCCTCACATCAGGATGGTCT

Downstream sequence

atcaccctctcatcgaggtcttccttgaccacactgcttaaaattgtccccctcgcctcaccttaccaccttcactgcctcatttctcctttgtgcttaa