VISDB Viral Integration Site DataBase

VIS ID

TVIS10017529

Fusion event

HBV-FOXP1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1831

Integrated sequence

GGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTC| |TGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAG

Chromosome

chr3

Cytoband

p13

Reference genome

Start

End

71229498/71180347 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-122-5p ; hsa-mir-34a-5p ; hsa-mir-335-5p ; hsa-mir-33a-5p ; hsa-mir-22-3p ; hsa-mir-1229-3p ; hsa-mir-320a ; hsa-mir-100-5p ; hsa-mir-9-5p ; hsa-mir-512-5p ; hsa-mir-218-5p ; hsa-mir-4276 ; hsa-mir-105-5p ; hsa-mir-7853-5p ; hsa-mir-578 ; hsa-mir-548aw ; hsa-mir-526b-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1181 ; hsa-mir-5195-5p ; hsa-mir-4480 ; hsa-mir-577 ; hsa-mir-497-3p ; hsa-mir-1277-5p ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-190a-3p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-let-7c-3p ; hsa-mir-486-5p ; hsa-mir-8485 ; hsa-mir-649 ; hsa-mir-335-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-6882-3p ; hsa-mir-27b-5p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-556-5p ; hsa-mir-512-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-367-5p ; hsa-mir-4639-5p ; hsa-mir-4517 ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-6507-3p ; hsa-mir-1264 ; hsa-mir-431-5p ; hsa-mir-561-3p ; hsa-mir-6821-5p

Nearest miRNA

hsa-let-7g/Upstream/2131312; hsa-mir-12124/Downstream/361623;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/114677, chr3-CpG: 155/Downstream/401075

Nearest cancer related gene

FOXP1(TSG, No orient, 0)

Upstream sequence

GAGGTGACAACGGAGAAGATCACCCTGTGGAACAGGGCCGTGCCGAGCACTTTCAGCTGGCTGGACACAGTCACAGTCACGCAGGATGGGTAAGCTCCCC

Downstream sequence

TTGGTTCTAGGTACTAATCCCATGGAAAATATAGAAAGACGGCAGCAAGGAACATTGAGACATGAAAGTCTTTGCCACGTGTAAAATCGTAGATGTTTTA