VISDB Viral Integration Site DataBase

VIS ID

TVIS10017530

Fusion event

HBV-KALRN integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1827

Integrated sequence

GACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCA| |CCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTT

Chromosome

chr3

Cytoband

q21.2

Reference genome

Start

End

123927560/124208713 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-186-3p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-5000-3p ; hsa-mir-4436a ; hsa-mir-8485 ; hsa-mir-1197 ; hsa-mir-329-3p ; hsa-mir-362-3p ; hsa-mir-6851-3p ; hsa-mir-5000-5p

Nearest miRNA

hsa-let-7g/Upstream/75688; hsa-mir-12124/Downstream/165619;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/174361, chr3-CpG: 16/Downstream/60166

Upstream sequence

CACATTCCTCACAGCTAAATTTTGTCATAAATTCTCTTTTATACAAGAAAAAAAGGCAACAGTTGTTTTCTTTTTTTTCCCAACAGGCTCTATTAATTAC

Downstream sequence

aagcactttgggaggctgtagcaggatgatcacttgaatgcaggaattcaaaaccaatctgggcaacatagggaggtcccatctctataaaaaatttaaa