VISDB Viral Integration Site DataBase

VIS ID

TVIS10017532

Fusion event

HBV-NPHP3 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1826

Integrated sequence

AGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATT

Chromosome

chr3

Cytoband

q22.1

Reference genome

Start

End

132411001/132692157 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-3117-5p ; hsa-mir-6757-3p ; hsa-mir-6773-5p ; hsa-mir-6724-5p ; hsa-mir-6832-5p ; hsa-mir-4451 ; hsa-mir-6508-3p ; hsa-mir-4640-5p ; hsa-mir-4726-5p ; hsa-mir-3124-3p ; hsa-mir-3121-5p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-3123 ; hsa-mir-3925-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-6878-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-3663-5p ; hsa-mir-3922-3p ; hsa-mir-3176 ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-4781-3p

Nearest miRNA

hsa-let-7g/Upstream/706226; hsa-mir-1224/Downstream/1675647;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/31358, chr3-CpG: 57/Downstream/29712

Upstream sequence

TCCACCACCCCCTGCTAAACTCACCTCCATGCTGGCTTGTTTGACCTTCTGCACCTCAAACACCCTGTGCGGGGTCCCCTGCTGGTAGTTGATGTAGTTC

Downstream sequence

ctgggagcaataggccataccatatagcctccatgtgtggtaggctgtaccatctagatttgtgtaagtacgctctacaatgctcacacaatgatacaat