Fusion event
HBV-CD14 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein;Polymerase;
Integrated sequence
CCGGTCTGGGGCGAAACTGCTCGGCACCGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATC| |CTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCGTCTGC
End
140011458/140631873 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10397/Upstream/68122; hsa-mir-103a-1/Downstream/15971;
Upstream sequence
TGAGCAGTAATATATAGTCACTCTTAATAGAACTTATTTGTATTCTCTCTCTCTTTCCCCATAAGAAACAAAAACGAAACAAGAAAATGTCATTCTCCAT
Downstream sequence
CCCTTGGAGCAGCACCAGGGTTCCCGACACCCCCACCGACAGGGTCGAACGTGCACAGGCTGGGACCACGCCGGAGTTCATTGAGCCCTCGTGGGGGAGG
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.