ABLIM3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017539
Fusion event
HBV-ABLIM3 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
core protein;X protein;
Start
1817
Integrated sequence
TGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGC| |AACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTA
Host Sequence
Chromosome
chr5
Cytoband
q32
Reference genome
GRCh37/hg19
Start
148637677/149258114 (Hg38)
End
148637677/149258114 (Hg38)
Location type
Intronic
Target gene
ABLIM3
miRNAs that regulate target gene
hsa-mir-214-3p
Nearest miRNA
hsa-mir-10397/Upstream/195705; hsa-mir-103a-1/Downstream/170804;
Nearest TSS
ENST00000502646/Upstream/5770; ENST00000508444/Downstream/13757;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/116210, chr5-CpG: 75/Downstream/13466
Upstream sequence
GAGCTGGCTCAAACGTCATGCAGACCTTCACCTTCTATGCGAGTGAAGACAAGCTGGAGAACAGGGGCAACTATGTCTTAGAGAAGATATCTGTGAGTAA
Downstream sequence
cactcattcaacaaatattcatcacacattccccaggctcaggcaccatgcaaggcacagggtgcccagagggaacatgcagcacccactgctgcctcca
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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