Fusion event
HBV-IMPG1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
GCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGG| |GAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAG
End
76731137/76021420 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10398/Upstream/592947; hsa-mir-10524/Downstream/2517843;
Upstream sequence
ATTTATGGTTTGGATAGGGAAAGGGGGACGTCAAGTCAAGGTTTAAAATAGAAAGATTCAGCCTTATTGGGTTTAAAAGAGAGAGGTGCACCCCGGGGCT
Downstream sequence
actcatatttggctcagaataaatctcttcaaatattttacagagttcgacaatttgtcgacaATGAGGACAGTGTTTCCCTTCTTCCACAATTAAATTC
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.