Fusion event
HBV-TAB3 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
core protein;X protein;
Integrated sequence
ACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCAC| |CTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTG
End
30899116/30880999 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-23c/Upstream/1306641; hsa-let-7f-2/Downstream/1702657;
Upstream sequence
TAAAAACAGACTCTAAGATCGCTCTGCACTCAACCCTATTCCCAAACCCTTTTAGCCCATATCTCATCTTATGTTCTGTCAATCCCTTTGATTTTTCGGT
Downstream sequence
tccctcaacaataatatataatgatctattcatacagtggaatagtatacagtaatgagaatgaacagtctacaactacatacgatataaatacatctca
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.