MSRA _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017548
Fusion event
HBV-MSRA integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;
Start
1629
Integrated sequence
CTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCC| |GACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGA
Host Sequence
Chromosome
chr8
Cytoband
p23.1
Reference genome
GRCh37/hg19
Start
10286162/10428652 (Hg38)
End
10286162/10428652 (Hg38)
Location type
3UTR
Target gene
MSRA
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-124-1/Upstream/525180; hsa-mir-10400/Downstream/238326;
Nearest TSS
ENST00000518652/Upstream/102184; ENST00000518098/Downstream/45913;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/23940, chr8-CpG: 19/Downstream/183633
Upstream sequence
GGGTCAATTAGAGTTCCTGTCCAGGGAATTTGGAATtgggatgggaagcggcagaaccttctccttttattttactggaaagtgaggctaggaaaagaaa
Downstream sequence
TTTATCTGTGCTCTCTGCCCGCCAGTGCCTTACAATTTGCAAACGTGTATAGCCTCAGTGACTCATTCGCTGAAATCCTTCGCTTTACCAAATCTAGACA
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate