VISDB Viral Integration Site DataBase

VIS ID

TVIS10017549

Fusion event

HBV-FFAR4 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1832

Integrated sequence

GGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCT| |GCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGC

Chromosome

chr10

Cytoband

q23.33

Reference genome

Start

End

95349281/93589524 (Hg38)

Location type

3UTR

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-640 ; hsa-mir-3692-5p ; hsa-mir-6778-3p ; hsa-mir-150-5p ; hsa-mir-1224-3p ; hsa-mir-186-3p ; hsa-mir-548av-3p ; hsa-mir-548s ; hsa-mir-340-5p ; hsa-mir-3926 ; hsa-mir-6765-3p ; hsa-mir-3190-5p ; hsa-mir-3065-5p ; hsa-mir-501-5p ; hsa-mir-500a-5p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-5089-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-500a-3p ; hsa-mir-6804-3p ; hsa-mir-3130-3p ; hsa-mir-1273g-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p

Nearest miRNA

hsa-mir-107/Upstream/3996697; hsa-mir-1287/Downstream/2474791;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/22173, chr10-CpG: 106/Downstream/11108

Upstream sequence

taacggaatcaaacggaattatcgaatggaatcgaagagaatcatcgaatggactcgaatggaatcatctaatggaatggaatggaataatccatggatt

Downstream sequence

ACTGTCAGCTTTTAGGAGGCAGGGATTGGTCTGCTTAATTTATCCTGAAGGAGCTGGGCAAGAGGCAGATGTTTCCGACCTCATACAGGTGCACCTCAGa