VISDB Viral Integration Site DataBase

VIS ID

TVIS10017552

Fusion event

HBV-CYP2C8 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1719

Integrated sequence

GTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTG| |TATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAA

Chromosome

chr10

Cytoband

q23.33

Reference genome

Start

End

96797077/95037320 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-1178-3p ; hsa-mir-6749-5p

Nearest miRNA

hsa-mir-107/Upstream/5444493; hsa-mir-1287/Downstream/1026995;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/491184, chr10-CpG: 63/Downstream/146118

Upstream sequence

catcactgaatggaatcgaatggattcattgaatggaatcagatgggatcatcgaatggacttgaatggaatcattgaatggactcgaaaggaatcatta

Downstream sequence

ACAacaggctgggtacgaggggcttggtcccaagcccagctcagacagcaactaactgacctttggcaagagcctcggtcacatcacttcCAACAAGAAA