VISDB Viral Integration Site DataBase

VIS ID

TVIS10017555

Fusion event

HBV-CYP2C8 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;Polymerase;

Start

2449

Integrated sequence

ACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGT| |TAGTATCCCTTGGACTCATAAGGTGGGAAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTGACTGGCAAACTCCCTCTTTTCCTCAC

Chromosome

chr10

Cytoband

q23.33

Reference genome

Start

End

96798798/95039041 (Hg38)

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-1178-3p ; hsa-mir-6749-5p

Nearest miRNA

hsa-mir-107/Upstream/5446214; hsa-mir-1287/Downstream/1025274;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/492905, chr10-CpG: 63/Downstream/144397

Upstream sequence

ttcacagccaaattctaccagaggtacaaagaggagctggtacgattctttctgaaactattccaaacaatagaaaaagaaggactcctctctaactcat

Downstream sequence

ACTGTATCTAAAAAGATTCTTAGAAATAAACCATGTGGCTTCTCAGGTTTATTCAACGATCAGTCCATCCAGCCCTCACTGAGCATCTTCTGCACGTAGC