Fusion event
HBV-FN1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
core protein;X protein;
Integrated sequence
AGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATT
End
216282041/215417318 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/1659159; hsa-mir-1244-1/Downstream/2483195;
Upstream sequence
ggggggggggggagggaggggggggtgagagggggggggggggggggggggggggggggggggggggggggggggggggagggggggggggggggggggg
Downstream sequence
GTACAATGTCTACACTTTTAAAATTAGTTTCAAATAAAGTCTAAATGAATAATTTCCAATAGTAGTGTCCTTGGAGAAGTTAAACATTTATGATTTTTTG
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.