VISDB Viral Integration Site DataBase

VIS ID

TVIS10017569

Fusion event

HBV-IGFBP5 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

458

Integrated sequence

TGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAG| |GTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCC

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

217543805/216679082 (Hg38)

Location type

splicing

Target gene

miRNAs that regulate target gene

hsa-mir-140-5p ; hsa-mir-331-3p ; hsa-mir-17-5p ; hsa-mir-211-5p ; hsa-mir-342-3p ; hsa-mir-548t-3p ; hsa-mir-548aa ; hsa-mir-548ap-3p ; hsa-mir-3613-3p ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-6507-5p ; hsa-mir-4689 ; hsa-mir-6858-5p ; hsa-mir-548t-5p ; hsa-mir-4796-3p ; hsa-mir-548az-5p ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-4726-3p ; hsa-mir-5000-5p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-1270 ; hsa-mir-1224-5p ; hsa-mir-3915 ; hsa-mir-5705 ; hsa-mir-616-3p ; hsa-mir-380-5p ; hsa-mir-563 ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-3928-3p ; hsa-mir-145-5p ; hsa-mir-4446-5p ; hsa-mir-4268 ; hsa-mir-7977 ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-4264 ; hsa-mir-4797-3p ; hsa-mir-6083 ; hsa-mir-4328 ; hsa-mir-4633-5p ; hsa-mir-532-5p ; hsa-mir-186-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-4758-5p ; hsa-mir-1238-5p ; hsa-mir-623 ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-1252-3p ; hsa-mir-3646 ; hsa-mir-204-5p ; hsa-mir-4770 ; hsa-mir-6088 ; hsa-mir-143-3p ; hsa-mir-203a-3p ; hsa-mir-297 ; hsa-mir-584-5p ; hsa-mir-567 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-411-3p ; hsa-mir-379-3p ; hsa-mir-4495 ; hsa-mir-5579-5p ; hsa-mir-3925-5p ; hsa-mir-4773 ; hsa-mir-625-3p ; hsa-mir-4797-5p ; hsa-mir-583 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-510-3p ; hsa-mir-4307 ; hsa-mir-548l ; hsa-mir-4531 ; hsa-mir-106a-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-380-3p ; hsa-mir-5571-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-5089-5p ; hsa-mir-6728-5p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-6740-5p ; hsa-mir-3190-3p ; hsa-mir-6077 ; hsa-mir-7-5p ; hsa-mir-3922-3p ; hsa-mir-3176 ; hsa-mir-5190 ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-892b ; hsa-mir-193a-3p ; hsa-mir-193b-3p ; hsa-mir-1229-3p ; hsa-mir-3119 ; hsa-mir-4719 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-5096 ; hsa-mir-587 ; hsa-mir-653-5p ; hsa-mir-197-3p ; hsa-mir-545-5p ; hsa-mir-4733-3p ; hsa-mir-1226-3p ; hsa-mir-501-5p ; hsa-mir-6830-3p ; hsa-mir-3124-3p ; hsa-mir-323b-3p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-6882-5p ; hsa-mir-1264 ; hsa-mir-197-5p

Nearest miRNA

hsa-mir-10b/Upstream/2920923; hsa-mir-1244-1/Downstream/1221431;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/44958, chr2-CpG: 28/Downstream/12997

Nearest cancer related gene

IGFBP5(TSG, No orient, 0)

Upstream sequence

AATGGGGGTAGAATCTTAGACAAATAGCAAAGGTAATAATTAAAGACCTAGTTTTATTTCTCATCAGTCTAAGCAGTCTATCAGTTTGGAAAAAACATCA

Downstream sequence

CAGGAGAAGGAGCCGGAGGGTCAGCCCCCGTGGGCCAAGGTGCACACGGCCAGAGCCCAGGGCTGGGCAGTTTGGGGTGAGGGGAGTAATAAAGGCTGAA