VISDB Viral Integration Site DataBase

VIS ID

TVIS10017570

Fusion event

HBV-PSMD1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1786

Integrated sequence

CGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAG| |GCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTG

Chromosome

chr2

Cytoband

q37.1

Reference genome

Start

End

231984742/231120028 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-mir-1180-3p ; hsa-mir-423-3p ; hsa-mir-346 ; hsa-mir-331-3p ; hsa-mir-149-5p ; hsa-mir-744-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-8057 ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-4284 ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3189-3p ; hsa-mir-212-5p

Nearest miRNA

hsa-mir-10b/Upstream/3647841; hsa-mir-1244-1/Downstream/242680;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/62770, chr2-CpG: 51/Downstream/78431

Upstream sequence

CATTTTTGTTACATGCCACTTCCAAGGCTCACCAGATGCGCTGGCTGACTGCTGGTGAGTGCTGTTCTCGCCCTGCCTTTGTCTTTGATCATACGCTGCT

Downstream sequence

tgcaactctgtcttccgggttcaagctattctcctgcctcagtctcccgagtagctgggactacaggcgcgtaccaccatgcccagctaatttttgtatt