VISDB Viral Integration Site DataBase

VIS ID

TVIS10017571

Fusion event

HBV-GNAS integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1757

Integrated sequence

GAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGA| |TTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCC

Chromosome

chr20

Cytoband

q13.32

Reference genome

Start

End

57435821/58860766 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-320b ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-331-3p ; hsa-mir-320a ; hsa-mir-17-5p ; hsa-let-7b-5p ; hsa-mir-205-5p ; hsa-mir-212-5p ; hsa-mir-188-3p ; hsa-mir-376a-3p ; hsa-mir-376b-3p ; hsa-mir-532-3p ; hsa-mir-5196-3p ; hsa-mir-142-3p ; hsa-mir-875-3p ; hsa-mir-1299 ; hsa-mir-4280 ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4540 ; hsa-mir-3978 ; hsa-mir-4768-3p ; hsa-mir-6073 ; hsa-mir-432-3p ; hsa-mir-136-5p ; hsa-mir-432-5p ; hsa-mir-377-5p ; hsa-mir-218-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-219b-5p ; hsa-mir-888-3p ; hsa-mir-4735-3p ; hsa-mir-18b-5p ; hsa-mir-18a-5p ; hsa-mir-3665 ; hsa-mir-6804-5p ; hsa-mir-6786-3p ; hsa-mir-203a-3p ; hsa-mir-125a-3p ; hsa-mir-6755-5p ; hsa-mir-4519 ; hsa-mir-4274 ; hsa-mir-1252-3p ; hsa-mir-199a-3p ; hsa-mir-199b-3p ; hsa-mir-3129-5p ; hsa-mir-5706 ; hsa-mir-4782-5p ; hsa-mir-516b-5p ; hsa-mir-6128 ; hsa-mir-6838-3p ; hsa-mir-4642 ; hsa-mir-6771-5p ; hsa-mir-425-3p ; hsa-mir-3622b-5p ; hsa-mir-6847-3p ; hsa-mir-4793-5p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p

Nearest miRNA

hsa-mir-103a-2/Upstream/42453; hsa-mir-1-1/Downstream/1447708;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/4582, chr20-CpG: 342/Downstream/27831

Nearest cancer related gene

GNAS(OG, No orient, 0)

Upstream sequence

taaataaataCTCTCTGATTCTGCTAATTCCTCTAATCTTAAACATTCCTCTTTTAGGAAAGTGGACCATAAAGGCTGTTACTGCCAATGGAAGGCATCT

Downstream sequence

tctcctgcctcagcctctcgaatagctgggattacagacatgcaccaccacacctggataattttttgtatttttagtagagatggggtttcaccatgtt