Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017573
Fusion event
HBV-CLTCL1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
X protein;
Start
1805
Integrated sequence
CTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCA| |CCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGA
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
Start
End
19233374/19245851 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-3198-1/Upstream/1264890; hsa-let-7a-3/Downstream/717902;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/66548, chr22-CpG: 62/Downstream/45297
Upstream sequence
ataacaataaaatatgaggccttttgtgcctcacttttttcatttagtaagtttttgaggtttacctatgtgtagcatgtatcagtacttcatttttagg
Downstream sequence
gttaaataatgtcccactgtatggatacaccacaacttgtttatccactcatttgctggtgaacatttgggctgtttctaccttttggttattataaaaa
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.