VISDB Viral Integration Site DataBase

VIS ID

TVIS10017574

Fusion event

HBV-ATG7 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

458

Integrated sequence

TGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAG| |GTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCC

Chromosome

chr3

Cytoband

p25.3

Reference genome

Start

End

11596321/11554847 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-320c ; hsa-mir-96-5p ; hsa-mir-4687-5p ; hsa-mir-4726-5p ; hsa-mir-6749-3p ; hsa-mir-4640-5p ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-3918 ; hsa-mir-4733-3p ; hsa-mir-6895-5p ; hsa-mir-6753-5p ; hsa-mir-4708-3p ; hsa-mir-6826-5p ; hsa-mir-3922-5p ; hsa-mir-451b ; hsa-mir-4753-5p ; hsa-mir-154-5p ; hsa-mir-3127-5p ; hsa-mir-6802-3p ; hsa-mir-6879-3p ; hsa-mir-4518 ; hsa-mir-1266-5p ; hsa-mir-6783-5p ; hsa-mir-4640-3p ; hsa-mir-34a-5p ; hsa-mir-210-3p ; hsa-mir-106a-5p

Nearest miRNA

hsa-mir-12127/Upstream/1160285; hsa-let-7g/Downstream/3941392;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/66201, chr3-CpG: 22/Downstream/13816

Upstream sequence

tttcttggggtggatttcttaggcctttttacaagtaggatcatgttgtttacaaataaagactgacttcttttccagtctggatgcccttcttctttcc

Downstream sequence

GCCCCGCTGTGGGGCTGACTTCTCCCCGGCCGCCTGCTGAGGAGCTCTCCATCGCCAGAGCAGGACTGCTGACCCCAGGCCTGGTGATTCTGGGCCCCTC