VISDB Viral Integration Site DataBase

VIS ID

TVIS10017577

Fusion event

HBV-ARL15 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1715

Integrated sequence

CACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGAC| |TGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCAT

Chromosome

chr5

Cytoband

q11.2

Reference genome

Start

End

53268149/53972319 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-744-5p ; hsa-mir-155-5p ; hsa-mir-142-3p ; hsa-mir-7-5p ; hsa-mir-222-5p ; hsa-mir-3177-5p ; hsa-mir-7110-3p ; hsa-mir-4797-3p ; hsa-mir-4264 ; hsa-mir-936 ; hsa-mir-648 ; hsa-mir-199b-3p ; hsa-mir-199a-3p ; hsa-mir-3129-5p ; hsa-mir-6873-3p ; hsa-mir-6817-3p

Nearest miRNA

hsa-mir-10397/Upstream/20720; hsa-mir-103a-1/Downstream/1198213;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/411279, chr5-CpG: 59/Downstream/337783

Upstream sequence

aaaaaaaaaaaaaaaaaaaaaCTTTGGGGGATGTTTGGCGGGTTCTCTCCGCAGTCCCTGCGGACCCACGCTCCAGGAAGGAGCTCCCGGCTGCGCACAC

Downstream sequence

TGGATCATATTTTCAATACCACAATTATTTTCATTATTTTAGTTTGTTCCCCAGTAGCAcagtatattatagtagaagatatgctggactttgactcaga