VISDB Viral Integration Site DataBase

VIS ID

TVIS10017578

Fusion event

HBV-ZDHHC14 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1814

Integrated sequence

CTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCA| |TGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCC

Chromosome

chr6

Cytoband

q25.3

Reference genome

Start

End

158034396/157613364 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-130b-3p ; hsa-mir-587 ; hsa-mir-5581-3p ; hsa-mir-3140-3p ; hsa-mir-6872-3p ; hsa-mir-302f ; hsa-mir-451a ; hsa-mir-6511b-5p ; hsa-mir-676-5p ; hsa-mir-6811-5p

Nearest miRNA

hsa-mir-10398/Upstream/84164; hsa-mir-1913/Downstream/996343;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/20140, chr6-CpG: 26/Downstream/59414

Upstream sequence

ACACAGAGACGTAACCATATTACAAACTGTGGTTCTTTTAGGAACACTGAACAAAAACATCAAATTTGGACTTGCTATACAATGAAATTGCTAATTACTT

Downstream sequence

agtgctggtcatgaccagctaaatcaatttcatgactcactatttgatcacaacccttagtttaagaaatcctgGAATAAAGCGTAATTAGAGTAGCTCC