VISDB Viral Integration Site DataBase

VIS ID

TVIS10017581

Fusion event

HBV-ERRFI1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

323

Integrated sequence

AGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTTGCAGTCCCCAA| |CCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATG

Chromosome

chr1

Cytoband

p36.23

Reference genome

Start

End

8075501/8015441 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-200c-3p ; hsa-mir-193b-3p ; hsa-mir-429 ; hsa-mir-200b-3p ; hsa-mir-423-5p ; hsa-mir-378a-3p ; hsa-mir-18a-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-148a-3p ; hsa-mir-6083 ; hsa-mir-675-3p ; hsa-mir-448 ; hsa-mir-331-5p ; hsa-mir-125b-2-3p ; hsa-mir-380-3p ; hsa-mir-411-3p ; hsa-mir-379-3p ; hsa-mir-4495 ; hsa-mir-586 ; hsa-mir-4678 ; hsa-mir-140-3p ; hsa-mir-2355-5p ; hsa-mir-3914 ; hsa-mir-3922-5p ; hsa-mir-4427 ; hsa-mir-4457 ; hsa-mir-4724-5p ; hsa-mir-4731-3p ; hsa-mir-4753-5p ; hsa-mir-4801 ; hsa-mir-5585-3p ; hsa-mir-634 ; hsa-mir-6840-3p

Nearest miRNA

hsa-mir-12136/Upstream/1585545; hsa-mir-101-1/Downstream/851061;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/53275, chr1-CpG: 155/Downstream/10053

Nearest cancer related gene

ERRFI1(TSG, No orient, 0)

Upstream sequence

tggaaacgggatttcttcctattctgctagacagatgaattctcagtaacttccttgtgttgtgtgtattcaactcacagagttgaacgatcctttacac

Downstream sequence

GAAGCAGTTGCAGGCTCAGAATGGTTTCTATGTCTTTTAAAAGGATCTGGTCTTAGggtcaggcgtggtggctcatgcctgtaatcccagcactttggga