VISDB Viral Integration Site DataBase

VIS ID

TVIS10017587

Fusion event

HBV-MLLT6 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;Polymerase;

Start

1516

Integrated sequence

TCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCGTCTGCCGTTCCGGCCGA| |CCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACC

Chromosome

chr17

Cytoband

q12

Reference genome

Start

End

36872024/38715771 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-103a-3p ; hsa-mir-93-5p ; hsa-mir-16-5p ; hsa-mir-1303 ; hsa-mir-877-3p ; hsa-mir-23b-3p ; hsa-mir-4477a ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-377-3p ; hsa-mir-342-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-4643 ; hsa-mir-129-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-543 ; hsa-mir-3166 ; hsa-mir-4329 ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-1324 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-483-5p ; hsa-mir-4524b-3p

Nearest miRNA

hsa-mir-1180/Upstream/13440; hsa-mir-10226/Downstream/3920;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/9613, chr17-CpG: 83/Downstream/14084

Upstream sequence

AGAGGGAAGTTGCAATGAAACTAGTTGCATTGAAAGCCAGGATTTTCTGATGACTGGAACCCTAGTGAGGGTGCATGCTCTGCTCCTGAATGCATTGGTA

Downstream sequence

cctcctcttcttcctcctcctcttcctcctcctctGGGGGGCCCTTCCAGCCTGCAGGTGAGTGTGGGCATCCGGGAGGAAGCTGGGAGCAGGGAAAGCC