VISDB Viral Integration Site DataBase

VIS ID

TVIS10017588

Fusion event

HBV-P4HB integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

243

Integrated sequence

CTGCACCGAATATGGAGAGCACCACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACA| |GAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTTGCAGTCCCCAACCTCCAATCACTCACCAACC

Chromosome

chr17

Cytoband

q25.3

Reference genome

Start

End

79801120/81843244 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-210-3p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-484 ; hsa-mir-183-5p ; hsa-mir-92a-3p ; hsa-mir-188-5p ; hsa-mir-3672 ; hsa-mir-4520-3p ; hsa-mir-6516-3p ; hsa-mir-422a ; hsa-mir-378i ; hsa-mir-378h ; hsa-mir-378f ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-4638-3p ; hsa-mir-518c-5p ; hsa-mir-451b ; hsa-mir-514a-5p ; hsa-mir-548n ; hsa-mir-1252-5p ; hsa-mir-1294 ; hsa-mir-135b-3p ; hsa-mir-298 ; hsa-mir-3650 ; hsa-mir-3919 ; hsa-mir-4292 ; hsa-mir-4308 ; hsa-mir-4710 ; hsa-mir-4756-3p ; hsa-mir-4787-5p ; hsa-mir-483-5p ; hsa-mir-548e-5p ; hsa-mir-597-5p ; hsa-mir-6077 ; hsa-mir-6134 ; hsa-mir-642b-5p ; hsa-mir-668-3p ; hsa-mir-670-5p ; hsa-mir-6752-5p ; hsa-mir-6758-5p ; hsa-mir-6782-5p ; hsa-mir-6791-5p ; hsa-mir-6842-5p ; hsa-mir-6856-5p ; hsa-mir-7110-5p ; hsa-mir-7854-3p ; hsa-mir-887-3p

Nearest miRNA

hsa-mir-10226/Upstream/149375; hsa-mir-4525/Downstream/393424;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/1496, chr17-CpG: 17/Downstream/3139

Upstream sequence

AGGCTGAGAATTGCCCCCAGGTGAGTGGGACGCTTGGATGATGTACAGACTGACACACTGCACACCAGGGTGGGCTCACAGCTCTGTACTCATGCGTCAT

Downstream sequence

TCAGCTCCAGCATCCTTGGCCACCTCCCCACCCGGGAGTCAAGGGTCGTGGTTCTGCCTTGAACAGGCCACAGGCCGTGCTGTAGAGAGGCCAGTGGTCA