VISDB Viral Integration Site DataBase

VIS ID

TVIS10017593

Fusion event

HBV-PCK1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

170

Integrated sequence

AGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCTCCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAATATGGAGAGCACCACAT| |CAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCT

Chromosome

chr20

Cytoband

q13.31

Reference genome

Start

End

56140866/57565810 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-33b-5p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-4482-3p ; hsa-mir-7159-3p ; hsa-mir-627-3p ; hsa-mir-330-3p ; hsa-mir-7151-5p ; hsa-mir-3163 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-8064 ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-26a-1-3p ; hsa-mir-129-5p ; hsa-mir-1297 ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-3650 ; hsa-mir-4465 ; hsa-mir-5697

Nearest miRNA

hsa-mir-103a-2/Upstream/244219; hsa-mir-1-1/Downstream/1251805;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/40616, chr20-CpG: 39/Downstream/86386

Upstream sequence

CCACCACAAATCCCGTGCCCACTCTTTCCACTGGCCCAGGCCCAGCTCACTACCTTTCTTAGAGCCCCTTTCCGACTACGCTCCCTTCTGTCCCTTCTCA

Downstream sequence

CCTGAGTGCTTTACCTTTAAAATCATTCCCTTTCCCATCCATAAGGTGCAGTAGGAGCAAGAGAGGGCAAGTGTTCCCAAATTGACGCCACCATAATAAT