ALDH1L1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017596
Fusion event
HBV-ALDH1L1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
Polymerase;
Start
1120
Integrated sequence
GCTCCCTTTACACAATGTGGTTACCCAGCATTAATGCCTTTGTATGCATGTATACAAGCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTC| |TGTGTAAACAATATCTGAACCTTTACCCCGTTGCTCGGCAACGGTCAGGTCTTTGCCAAGTATTTGCTGACGCAACCCCCACTGGTTGGGGCTTGGCCAT
Host Sequence
Chromosome
chr3
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
125836916/126118073 (Hg38)
End
125836916/126118073 (Hg38)
Location type
Exonic
Target gene
ALDH1L1
Nearest miRNA
hsa-let-7g/Upstream/327521; hsa-mir-12124/Downstream/1457193;
Nearest TSS
ENST00000440867/Upstream/2571; ENST00000502278/Downstream/38610;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/33658, chr3-CpG: 73/Downstream/61746
Upstream sequence
TACAGCCTATGCAACAACATACTTGTGACCAATTCTACATACAGATCATGATTTGCATAGCTTTCCTTTGTGTCAAAAAGAAACCAGGGCTATGTCCTTT
Downstream sequence
GAGAGTCTCTGGCCGACCAGGGAGCCTGTGGGCGGGAGGGAGGGGGGAATCAGAGTGGTCCCCCTGGTGCTGGGGAGGCAGGAGCCCACCTCCAGGACTG
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate