Fusion event
HBV-ALB integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
core protein;
Integrated sequence
GCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGC| |TTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGTGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCT
End
74283366/73417649 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/7140721; hsa-mir-1243/Downstream/3155919;
Upstream sequence
GGCGACCATGCTTTTCAGCTCTGGAAGTCGATGAAACATACGTTCCCAAAGAGTTTAATGCTGAAACATTCACCTTCCATGCAGATATATGCACACTTTC
Downstream sequence
TGCCCTGTGCAGAAGACTATGTGAGTCtttaaaaaaatataataaattaataatgaaaaaattttaCCTTTAGATATTGATAATGCTAGCTTTCATAAGC
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.