Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017605
Fusion event
HBV-AGT integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
X protein;
Start
1691
Integrated sequence
CACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACC| |GACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATA
Host Sequence
Chromosome
chr1
Cytoband
q42.2
Reference genome
End
230846276/230710530 (Hg38)
Location type
Exonic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-1/Upstream/2248378; hsa-mir-1182/Downstream/309298;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/67683, chr1-CpG: 119/Downstream/157355
Upstream sequence
CAAACAGAGAACTGTTTCCTCAAACGATCCACTTGCCTTTTATTAGTTGCTAAATAGACAAAGCTCCGACTAAGAGGAATCTAATTAGCTATTTGTAATT
Downstream sequence
tcagagaattcctgcatattaaccaggataatttcccttttattggctgaaaatcaactaattagaagtcttaattatatcaacaaaatccttatagttt
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.