Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017606
Fusion event
HBV-H2AFY2 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
X protein;
Start
1773
Integrated sequence
TCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTAC| |TGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCC
Host Sequence
Chromosome
chr10
Cytoband
q22.1
Reference genome
Start
End
71857842/70098086 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1265/Upstream/2694676; hsa-mir-107/Downstream/1692661;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/44149, chr10-CpG: 71/Downstream/34250
Upstream sequence
taaccataatcaattggtattgaatggaattgtcatccaatggaattcaaaggaatcatcatcaaatggaaccgaatggaatcctcattgaatggaaatg
Downstream sequence
TCCAACAACACAACTCCCATAAAGATGTGATCAGGGACTCCCTTTGCAAGTCTACGATTTCTCTGTAAATACAAGCTTCTTAAGTGTCTTTAGTCTGTCT
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.