VISDB Viral Integration Site DataBase

VIS ID

TVIS10017608

Fusion event

HBV-RPS25 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

482

Integrated sequence

CTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTCCTCTAC| |TTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCTCGTGTTGCTGTACAAAACCTTC

Chromosome

chr11

Cytoband

q23.3

Reference genome

Start

End

118888688/119017978 (Hg38)

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-218-5p ; hsa-mir-92a-3p

Nearest miRNA

hsa-mir-10392/Upstream/107191; hsa-let-7a-2/Downstream/294972;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/19484, chr11-CpG: 91/Downstream/190

Upstream sequence

cggcctggacgagagcaacactccgtctcaaaaaaaaaaagaaaagaaaagaaaCGCTGTGTCTGCTTCAGTCTATGGAGTCATAACATTTTGTGCGTCA

Downstream sequence

TCTCAGAGCTATGTGGTGTGTGTGCTGTCTCTGTTCCCATGTCTCTCTACCGTCACATCACCCCTGCTCACTGTGTACCTGACTGATTCTGTCTTCAGGG