VISDB Viral Integration Site DataBase

VIS ID

TVIS10017611

Fusion event

HBV-MPG integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

Polymerase;

Start

1066

Integrated sequence

AGACCTATTGATTGGAAAGTATGTCAACGAATTGTGGGGCTTCTGGGCTTTGCCGCTCCCTTTACACAATGTGGTTACCCAGCATTAATGCCTTTGTATG| |CATGTATACAAGCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTGAACCTTTACCCCGTTGCTCGGCAACGGTC

Chromosome

chr16

Cytoband

p13.3

Reference genome

Start

End

135492/85493 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-93-5p ; hsa-mir-92a-3p

Nearest miRNA

hsa-mir-6859-4/Upstream/68374; hsa-mir-11401/Downstream/449823;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/6861, chr16-CpG: 69/Downstream/52575

Upstream sequence

CATACTGAATGAACACACCTTCTGTGCTGGCATGTCTAAGTACCAAGAAGACACCTGCTATGGCGATGCGGGCAGTGCCTTTGCCGTTCACGACCTGGAG

Downstream sequence

CCAGCCGTGTCCTCAAGGACCGCGAGCTCTGCAGTGGCCCCTCCAAGCTGTGCCAGGCCCTGGCCATCAACAAGAGCTTTGACCAGAGGGACCTGGCACA