Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017612
Fusion event
HBV-HP integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
pre-S1/pre-S2/S;Polymerase;
Start
710
Integrated sequence
CCATCATCTTGGGCTTTCGCAAGATTCCTATGGGAGTGGGCCTCAGTCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGC| |TTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAACATCTTGAATCCCTTTTTACCGCTGTTACCAATTTT
Host Sequence
Chromosome
chr16
Cytoband
q22.2
Reference genome
Start
End
72094446/72060547 (Hg38)
Location type
Exonic
Target gene
Nearest miRNA
hsa-mir-1225/Upstream/2030125; hsa-mir-11401/Downstream/4808389;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/51558, chr16-CpG: 15/Downstream/32683
Upstream sequence
CCCACAGGGGACGGGGCTTGCGTCTTGCTGCGAGCACTGGAGCCCCTGGAAGGTCTGGAGACCATGCGTCAGCTTCGCAGCACCCTCCGGAAAGGCACCG
Downstream sequence
TGACCATCTGAAGTATGTCATGCTGCCTGTGGCTGACCAAGACCAATGCATAAGGCATTATGAAGGCAGCACAGTCCCCGAAAAGAAGACACCGAAGAGC
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.