VISDB Viral Integration Site DataBase

VIS ID

TVIS10017616

Fusion event

HBV-CCBE1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1630

Integrated sequence

TCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCG| |ACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGAC

Chromosome

chr18

Cytoband

q21.32

Reference genome

Start

End

57181117/59513885 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-4443 ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-3613-3p ; hsa-mir-6807-5p ; hsa-mir-3940-3p ; hsa-mir-4279 ; hsa-mir-6778-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-4740-3p ; hsa-mir-1207-3p ; hsa-mir-646 ; hsa-mir-122-3p ; hsa-mir-552-5p ; hsa-mir-2355-3p ; hsa-mir-4646-3p ; hsa-mir-676-3p ; hsa-mir-6852-3p ; hsa-mir-4286 ; hsa-mir-3909 ; hsa-mir-6749-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-1208 ; hsa-mir-6760-3p ; hsa-mir-548j-3p ; hsa-mir-548x-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-6875-3p ; hsa-mir-6883-3p ; hsa-mir-4778-3p ; hsa-mir-5009-3p ; hsa-mir-3121-3p ; hsa-mir-6881-3p ; hsa-mir-6873-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-4326 ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-4277 ; hsa-mir-584-3p ; hsa-mir-330-3p ; hsa-mir-4524a-3p

Nearest miRNA

hsa-mir-1-2/Upstream/1062727; hsa-mir-5011/Downstream/7567699;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/154348, chr18-CpG: 119/Downstream/182597

Upstream sequence

TATTCTTGAATGGGGCAAGGCTTTTGAAATTAGAATGCTTCAACCCAGGAAGACAAAGACTAAAATAAGATACCATTAAAGCATATAAAATTATGATGTT

Downstream sequence

GAGAGAAGACCCCCTATGCCACACTTGGGCCATCACGGGCTAGCTACTGGAGGAACAGGGGACTTGCACAGCTCTGCTGATATGCAGTTCAGCCTGCAGG